Description
Product Characteristics: SUPV3L1 (Suv3 Like RNA Helicase) is a Protein Coding gene. Diseases associated with SUPV3L1 include Uveoparotid Fever and Neuropathy, Hereditary Motor And Sensory, Russe Type. Gene Ontology (GO) annotations related to this gene include RNA binding.
Target Information: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria\, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA (By similarity)